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Then, the rate-limiting enzyme in arginine synthesis, argininosuccinate synthetase 1 (ASS1), catalyzes the conversion of citrulline and aspartate into argininosuccinate, which is then cleaved into arginine and fumarate by argininosuccinate lyase (ASL) (Figure 1)

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They bypass digestion to provide 100% absorption, replenishing natural antioxidant levels that protect against toxins, stress, and free-radical damage